Effect of the withdrawal of anti-thyroid treatment on the kynetics of iodine for the radioiodine therapy for autoimmune hyperthyroidism
- Conditions
- Autoimmune hyperthyroidism (Graves-Basedow disease)MedDRA version: 14.1Level: HLGTClassification code 10043739Term: Thyroid gland disordersSystem Organ Class: 10014698 - Endocrine disordersTherapeutic area: Diseases [C] - Hormonal diseases [C19]
- Registration Number
- EUCTR2012-003579-21-IT
- Lead Sponsor
- FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Adult patients, caucasian, asiatic, hispanic, male and female, aged 18-75 years, smokers and non smokers. Patients affected by Graves disease of every duration with normalization of free thyroid hormones at least from one month with anti-thyroid drug, without or with inactive orbitopathy (CAS<4)
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 25
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 5
Exclusion Criteria
Active Graves orbitopathy (CAS>3), severe Graves orbitopathy (optic neuropathy). Familiarity for arrhytmic cardiopathy. Pregnancy. Informed consent denied.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method