Resistance Exercise and Cognition in People With Type 1 Diabetes

Not Applicable

Recruiting

• Conditions: type1diabetes
• Interventions: Behavioral: Habitual Physical Activity; Behavioral: Morning Exercise; Behavioral: Afternoon Exercise

• Registration Number: NCT05963152
• Lead Sponsor: Dasman Diabetes Institute

Brief Summary

The aim of the current study is to determine the effects of resistance exercise on performance of the Paced Auditory Serial Addition Test and the Colour Trails Test.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-07-07
• Study First Submitted QC: 2023-07-18
• Study Start: 2023-07-20
• Study First Posted: 2023-07-27
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-07
• Last Update Posted: 2023-09-08
• Primary Completion: 2024-08-01
• Study Completion: 2024-08-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Physician confirmed type 1 diabetes for at least 1 year
• Stable insulin therapy for 3 months prior to the study

Exclusion Criteria

• BMI of 45 or higher
• BP of 160/100mmHg or higher
• autonomic neuropathy
• severe proliferative retinopathy
• joint or limb injuries preventing weight-bearing activity
• autonomic neuropathy
• severe proliferative retinopathy
• any other medical condition that prevents participants from exercising safely.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Habitual Physical Activity	Habitual Physical Activity
Morning exercise	Morning Exercise	Exercise training between 6-10am
Afternoon exercise	Afternoon Exercise	Exercise training between 4-8pm

Primary Outcome Measures

Name	Time	Method
Chronic change in Paced Auditory Serial Addition Test (PASAT) score	Change from baseline to 12 weeks	Measured using the standardised Paced Auditory Serial Addition Test (PASAT) score ranging from 0-60 with a higher score meaning a better outcome
Chronic change in Colour Trails Test score	Change from baseline to 12 weeks	Measured using the standardised Colour Trails Test, with score based on completion time (0-240s), number of errors, error type, and number of prompts with a shorter completion time and lower number of errors and prompts indicating a better outcome

Secondary Outcome Measures

Name	Time	Method
Baseline acute change in Paced Auditory Serial Addition Test (PASAT) score	Change from before (0 hour) to 1 hour post exercise during week 1	Measured using the standardised Paced Auditory Serial Addition Test (PASAT) during the first exercise session, score ranging from 0-60 with a higher score meaning a better outcome
12 week acute change in Paced Auditory Serial Addition Test (PASAT) score	Change from before (0 hour) to 1 hour post exercise during week 12	Measured using the standardised Paced Auditory Serial Addition Test (PASAT) during the last exercise session, score ranging from 0-60 with a higher score meaning a better outcome
Baseline acute change in Colour Trails Test score	Change from before (0 hour) to 1 hour post exercise during week 1	Measured using the standardised Colour Trails Test during the first exercise session, with score based on completion time (0-240s), number of errors, error type, and number of prompts with a shorter completion time and lower number of errors and prompts indicating a better outcome
12 week acute change in Colour Trails Test score	Change from before (0 hour) to 1 hour post exercise during week 12	Measured using the standardised Colour Trails Test during the last exercise session, with score based on completion time (0-240s), number of errors, error type, and number of prompts with a shorter completion time and lower number of errors and prompts indicating a better outcome

Trial Locations

Locations (1)

Dasman Diabetes Institute; 🇰🇼 Kuwait City, Kuwait