The Effects of Resistance Exercise on Cognition in People With Type 1 Diabetes: a Randomised Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- type1diabetes
- Sponsor
- Dasman Diabetes Institute
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- Chronic change in Paced Auditory Serial Addition Test (PASAT) score
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of the current study is to determine the effects of resistance exercise on performance of the Paced Auditory Serial Addition Test and the Colour Trails Test.
Investigators
Dr. Ebaa Al Ozairi
Chief Medical Officer
Dasman Diabetes Institute
Eligibility Criteria
Inclusion Criteria
- •Physician confirmed type 1 diabetes for at least 1 year
- •Stable insulin therapy for 3 months prior to the study
Exclusion Criteria
- •BMI of 45 or higher
- •BP of 160/100mmHg or higher
- •autonomic neuropathy
- •severe proliferative retinopathy
- •joint or limb injuries preventing weight-bearing activity
- •autonomic neuropathy
- •severe proliferative retinopathy
- •any other medical condition that prevents participants from exercising safely.
Outcomes
Primary Outcomes
Chronic change in Paced Auditory Serial Addition Test (PASAT) score
Time Frame: Change from baseline to 12 weeks
Measured using the standardised Paced Auditory Serial Addition Test (PASAT) score ranging from 0-60 with a higher score meaning a better outcome
Chronic change in Colour Trails Test score
Time Frame: Change from baseline to 12 weeks
Measured using the standardised Colour Trails Test, with score based on completion time (0-240s), number of errors, error type, and number of prompts with a shorter completion time and lower number of errors and prompts indicating a better outcome
Secondary Outcomes
- Baseline acute change in Paced Auditory Serial Addition Test (PASAT) score(Change from before (0 hour) to 1 hour post exercise during week 1)
- 12 week acute change in Paced Auditory Serial Addition Test (PASAT) score(Change from before (0 hour) to 1 hour post exercise during week 12)
- Baseline acute change in Colour Trails Test score(Change from before (0 hour) to 1 hour post exercise during week 1)
- 12 week acute change in Colour Trails Test score(Change from before (0 hour) to 1 hour post exercise during week 12)