The Effects of Resistance Exercise on Cognition in People With Type 1 Diabetes: a Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- Chronic change in Paced Auditory Serial Addition Test (PASAT) score
研究概览
简要总结
The aim of the current study is to determine the effects of resistance exercise on performance of the Paced Auditory Serial Addition Test and the Colour Trails Test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Physician confirmed type 1 diabetes for at least 1 year
- •Stable insulin therapy for 3 months prior to the study
排除标准
- •BMI of 45 or higher
- •BP of 160/100mmHg or higher
- •autonomic neuropathy
- •severe proliferative retinopathy
- •joint or limb injuries preventing weight-bearing activity
- •autonomic neuropathy
- •severe proliferative retinopathy
- •any other medical condition that prevents participants from exercising safely.
结局指标
主要结局
Chronic change in Paced Auditory Serial Addition Test (PASAT) score
时间窗: Change from baseline to 12 weeks
Measured using the standardised Paced Auditory Serial Addition Test (PASAT) score ranging from 0-60 with a higher score meaning a better outcome
Chronic change in Colour Trails Test score
时间窗: Change from baseline to 12 weeks
Measured using the standardised Colour Trails Test, with score based on completion time (0-240s), number of errors, error type, and number of prompts with a shorter completion time and lower number of errors and prompts indicating a better outcome
次要结局
- Baseline acute change in Paced Auditory Serial Addition Test (PASAT) score(Change from before (0 hour) to 1 hour post exercise during week 1)
- 12 week acute change in Paced Auditory Serial Addition Test (PASAT) score(Change from before (0 hour) to 1 hour post exercise during week 12)
- Baseline acute change in Colour Trails Test score(Change from before (0 hour) to 1 hour post exercise during week 1)
- 12 week acute change in Colour Trails Test score(Change from before (0 hour) to 1 hour post exercise during week 12)
研究者
Dr. Ebaa Al Ozairi
Chief Medical Officer
Dasman Diabetes Institute