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临床试验/NCT02696694
NCT02696694已完成不适用

Impact of Serum Progesterone Levels on the Day of Embryo Transfer on the Success Rate in Egg Donation Cycles Under Hormonal Replacement

Instituto Valenciano de Infertilidad, IVI VALENCIA1 个研究点 分布在 1 个国家目标入组 242 人开始时间: 2016年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
242
试验地点
1
主要终点
mid-luteal serum progesterone level

研究概览

简要总结

This study aims to investigate the impact of serum progesterone concentrations on the day of embryo transfer in egg donation cycles under hormonal replacement therapy. As secondary outcomes, the investigators will investigate if endometrial volume measured by three-dimensional (3D) ultrasound on the day of embryo transfer is related with progesterone levels and with chances of pregnancy.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
25 Years 至 50 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Age<50 yo
  • BMI < 30Kg/m2
  • Hormonal replacement cycle
  • Endometrial thickness >6.5 mm during proliferative phase
  • Transfer of one or two blastocyst grade A-B according to ASEBIR

排除标准

  • Uterine pathology
  • Cryptozoospermia
  • Severe implantation failure (>6 GQ embryos transferred without success)

结局指标

主要结局

mid-luteal serum progesterone level

时间窗: one year

次要结局

  • endometrial volume(one year)

研究者

发起方
Instituto Valenciano de Infertilidad, IVI VALENCIA
申办方类型
Other
责任方
Principal Investigator
主要研究者

Elena Labarta

Elena Labarta, MD, PhD

Instituto Valenciano de Infertilidad, IVI VALENCIA

研究点 (1)

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