跳至主要内容
临床试验/NCT04839627
NCT04839627已完成不适用

Impact of Serum Progesterone Levels on the Day of Fresh and Frozen Embryo Transfer on the Ongoing Pregnancy Rates

Hospital St. Joseph, Marseille, France1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2021年6月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
250
试验地点
1
主要终点
Serum progesterone levels on the day of embryo transfer

研究概览

简要总结

Serum progesterone levels prepare the endometrium for implantation and play an important role during embryo transfer (ET). In clinical practice, luteal phase support progesterone supplementation is systematically offered to all women undergoing medically assisted procreation (AMP), independently of ET conditions (fresh and frozen).

The investigators propose to perform a prospective cross-sectional single-center cohort study to measure progesterone levels on the day of the ET on all AMP cycles and to compare these levels between active pregnancies and ET unsuccessful cycles. They will determine progesterone threshold levels corresponding to successful attempts in all ET strategies (fresh and frozen) as well as clinical and biological risk factors leading to luteal phase deficiency during ET. They could therefore individualize progesterone supplementation according to patient's needs.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • planned embryo transfer
  • signed informed consent

排除标准

  • patients falsely included, major inclusion criteria not respected
  • lack of social insurance
  • refusal to participate in the research

结局指标

主要结局

Serum progesterone levels on the day of embryo transfer

时间窗: During the procedure

µg/L

次要结局

  • pregnancy rate(1 month after procedure)

研究者

发起方
Hospital St. Joseph, Marseille, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验