Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 198
- 试验地点
- 1
研究概览
简要总结
The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 55 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
- •18-55 years old
排除标准
- •Past history affecting CNS
- •Invalidating sensory disorders
- •Intake of psychotropic drugs, except for patients
- •Intake of benzodiazepines
研究组 & 干预措施
Arm 1
Healthy volunteers
干预措施: Experimental psychology methods (computer tests) (Behavioral)
Arm 2
Schizophrenia with history of delusions of control
干预措施: Experimental psychology methods (computer tests) (Behavioral)
Arm 3
Schizophrenia without history of delusions of control
干预措施: Experimental psychology methods (computer tests) (Behavioral)
Arm 4
Bipolar disorders
干预措施: Experimental psychology methods (computer tests) (Behavioral)
Arm 5
Matched healthy controls
干预措施: Experimental psychology methods (computer tests) (Behavioral)
