Skip to main content
Clinical Trials/NCT04575688
NCT04575688
Enrolling by Invitation
Phase 4

A Randomized Controlled Trial Comparing a Periarticular Injection to a Popliteal Block for Pain Control in Ankle/Hindfoot Osteotomy or Fusion and Ankle Fractures

Campbell Clinic1 site in 1 country100 target enrollmentJuly 13, 2021

Overview

Phase
Phase 4
Intervention
Bupivicaine
Conditions
Foot Surgery
Sponsor
Campbell Clinic
Enrollment
100
Locations
1
Primary Endpoint
Visual Analog Score
Status
Enrolling by Invitation
Last Updated
4 months ago

Overview

Brief Summary

This study aims to determine the effectiveness and safety of two standard of care perioperative procedures for controlling pain following ankle and hindfoot osteotomy or fusion or ankle fracture repair.

Detailed Description

This is a prospective, randomized, controlled research study of two perioperative standards of care for managing post operative pain. The first standard of care procedure is the periarticular injection; the second is the popiteal block.

Registry
clinicaltrials.gov
Start Date
July 13, 2021
End Date
February 28, 2027
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Ankle or hindfoot osteotomy or ankle fracture repair
  • Surgery scheduled at Campbell Surgery Center (1410 Brierbrook Road, Germantown, TN 38138)
  • 18-80 years of age
  • ASA I-III with medical clearances as needed
  • Fluent ub verbal and written English
  • Willing and able to comply with study instruction and commit to all follow-up visits for theduration of the study
  • Willing and able to provide written consent

Exclusion Criteria

  • Diagnosed with chronic pain syndrome
  • History of allergic reactions to lidocaine, marcaine, Experal, bupivicaine, or other injectable anesthetic agents
  • Injury associated with workers' compensation
  • Surgery to be performed at a hospital
  • Diagnosed with peripheral neuropathy
  • Hbg A1C is \> 7 mg/dl in diabetic patients only
  • Long term (chronic) preoperative narcotic usage

Arms & Interventions

Popliteal Block

Subjects undergoing hindfoot osteotomy or fusion, ankle osteotomy or fusion, or ankle fracture repair will recieve a popliteal block by the anesthesiologist using 30 milliliters of bupivicaine 0.5 percent in the pre-operative area, prior to surgery, using an ultrasound machine for guidance.

Intervention: Bupivicaine

Periarticular Injection

Subjects undergoing hindfoot osteotomy or fusion, ankle osteotomy or fusion, or ankle fracture repair will recieve a periarticular injection by the surgeon using 10 milliliters of Exparel mixed with 10 milliliters of bupivicaine 0.5 percent at the end of the procedure.

Intervention: Exparel

Outcomes

Primary Outcomes

Visual Analog Score

Time Frame: Postoperative week 12

Patient reported pain score from zero to ten where zero is no pain and ten is the most pain

Evidence of motor block

Time Frame: Postoperative hour 3

Patient reported yes/no answer to survey question: "Are you able to wiggle your toes?"

Secondary Outcomes

  • Document pain medication prescribed immediately after surgery(Immediately after surgery)
  • Neuralgia symptoms: survey question(Postoperative week 12)
  • Pill count(Postoperative week 12)
  • Document pain medication prescribed at postoperative week 2(Postoperative week 2)
  • Document pain medication prescribed at postoperative week 6(Postoperative week 6)
  • Satisfaction with pain control: survey question(Postoperative week 12)
  • Document pain medication prescribed at postoperative week 12(Postoperative week 12)

Study Sites (1)

Loading locations...

Similar Trials