The impact of weight reduction on brain's energy homeostasis

• Conditions: Overweight , obesity; E66.00; E66.01; E66.02

• Registration Number: DRKS00009754
• Lead Sponsor: Sektion für Psychoneurobiologie Universität Lübeck

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-10-01
• Study Start: 2016-03-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

Body mass index >30

Exclusion Criteria

Body mass index < 30, acute or chronic physical and mental illness, current medication

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral energy content before and after weight loss (14 days). Cerebral energy content is determined by imaging (31 Phosphorus magnetic resonance spectroscopy): Before body weight loss (baseline) and after 14 days.

Secondary Outcome Measures

Name	Time	Method
Metabolic parameters (glucose, insulin, C-peptide, cortisol, ephinephrine, norephinephrine) before and after weight loss.