Measuring the increase in exhaled carbon dioxide in spontaneously breathing infants at birth, the RISE study

Not Applicable

Completed

• Conditions: eonatal resuscitation; Lung aeration at birth; Neonatal resuscitation; Reproductive Health and Childbirth - Childbirth and postnatal care; Reproductive Health and Childbirth - Complications of newborn; Respiratory - Normal development and function of the respiratory system

• Registration Number: ACTRN12615000174583
• Lead Sponsor: Prof Peter Davis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-02-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All inborn infants, term and preterm born at 35 weeks or later gestational age, who are not expected to require respiratory support at birth, are eligible for this study.

Exclusion Criteria

Infants will be excluded from analysis if they have a congenital abnormality or condition that might have an adverse effect on breathing or respiratory drive including: infants born to mothers receiving general anesthesia and congenital diaphragmatic hernia. Infants will also be excluded if their parents refuse to give consent to this study. During the study, if there are any signs of respiratory compromise, the study will be abandoned and ventilatory support given according to the Australian Neonatal Resuscitation guidelines.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome for this study will be measuring the exhaled carbon dioxide levels using the NM3 Respiratory Profile Monitor.[Exhaled carbon dioxide levels will be measured every minute for the first ten minutes of life, than once at 1-2 hours of life and once at 12-72 hours of life. ]