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Effect of allopurinol to prevent loss of muscle mass in immobilized subjects.

Phase 1
Conditions
Immobilized subjects.
Therapeutic area: Body processes [G] - Bones and nerves physological processes [G11]
Registration Number
EUCTR2011-003541-17-ES
Lead Sponsor
Instituo de Investigacion Sanitaria La Fe
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

Patients with grade II sprain.
Males.
Ages 20 to 40 years.
Patients not taking regular medication. The concept is understood not to take regular medication to all patients who chronically fail to take any medication in a timely manner regardless of whether they needed to take the last week or last month for a condition treatment on time.
All patients must have written full informed consent specifically for this study
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Liver and gastrointestinal disease.
Hipotiroismo untreated.
Alcohol and / or substance abuse.
Vitamin supplements.
Eating disorders.
Drugs that lower lipid levels.
Hypotensive drugs.
Smokers.
Athletes who perform strenuous exercise.
Mental disorders, depression or anxiety intensity. These diseases cause the patient unable to understand the nature or scope and possible consequences of the study.
Patients with any infectious process and / or inflammatory before collecting the sample.
Patients may not follow the protocol because of its lack of cooperation, inability to return to subsequent visits and there is little chance of completing the study procedures.
Hypersensitivity to allopurinol.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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