A Comparative Clinical study to evaluate the efficacy of Kalyanaka kshara and Vidangadi Gutika along with Shwadanshtradi kwath after Koshtha Shodhana in the Management of Mutrashmari (Urolithiasis).
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 80% Reduction In The Symptoms Of Mutrashmari
研究概览
简要总结
Patient suffering from HTN, DM, asthma, and anaesthetic drugs sensitivity etc needs some alternative management to avoid surgical procedures. These factors invite the need of an effective medicinal treatment for urolithiasis with least chances of recurrence. Though different Aachaaryas have been described use of various medicines along with the Kshaara Dravyas, Kwathas, Ras aushadhis, etc. No work is done on the concept of Koshtha shodhana followed by Shwadanshtradi kwath ( RefBhaishajya ratnavali ashmari chikitsa) with Kalyanaka kshara and with Vidangadi Gutika. Also, usage of Kalyanaka Kshara(as mentioned in its Phal shruti in Ashtanga Hridaya Arsha chikitsa) in Mutrashmari is not explored. Vidangadi Gutika mentioned in “Abhinava Chintamani – Ashmari Chikitsa†vii is undertaken in this research study as it is an unexplored formulation. In the study kshara was selected due to its multiple properties Chedana (Excision), Bhedana (Incision), Lekhana (Scraping), Shodhana (Cleaning), Ropana (Healing) etc.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Kidney stone size up to 10 mm and/or
- •Ureteric Stone size up to 8 mm and/or
- •Radiographic and /or USG evidence of the stone.
排除标准
- •Chronic Renal failure.
- •Gross Hydronephrosis.
- •Cases which require surgical intervention.
- •Severe Hematuria.
- •Kidney stone and Bladder Stone size more than 10 mm.
- •Ureteric stone Size more than 8 mm
- •Known cases of Malignancy, Tuberculosis.
- •Known cases of HIV (Human Immunodeficiency Virus), VDRL (Venereal Disease Research Laboratory) and Hepatitis-B positive.
- •Patients with HbA1C ≥ 9 And Grade 3 hypertension: SBP greater than or equal to 180mmHg and/or DBP greater than or equal to 110mmHg.
- •Patients with previously known allergy of any of the interventional drugs or ingredients.
- •Patients not willing for trial and follow up.
结局指标
主要结局
80% Reduction In The Symptoms Of Mutrashmari
时间窗: 0th Day , 14th Day ,28th Day , 43rd Day
次要结局
- Reduction In The Size Of Stone(0th Day AND 43rd Day)
研究者
Vidhi Jain
All India Institute Of Ayurveda