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Clinical Trials/NCT00975559
NCT00975559
Completed
N/A

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

Mayo Clinic1 site in 1 country190 target enrollmentSeptember 2003

Overview

Phase
N/A
Intervention
Not specified
Conditions
Coronary Endothelial Dysfunction
Sponsor
Mayo Clinic
Enrollment
190
Locations
1
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

The aim of this study is to measure how different people respond to mental stress. The investigators will measure if there are differences in cardiovascular responses to mental stress among different groups of subjects. In one part of the study the investigators will compare the cardiovascular responses to mental stress between healthy women and healthy men. In another part of the study, the investigators will compare the cardiovascular responses to mental stress between women with apical ballooning syndrome and healthy post-menopausal women. The investigators hypothesize that healthy men will have an increased vascular response to and decreased endothelial function in response to to mental stress, compared to health women. Furthermore, the investigators hypothesize that women with apical ballooning syndrome will have an increased vascular response to and decreased endothelial function in response to mental stress.

Registry
clinicaltrials.gov
Start Date
September 2003
End Date
April 2011
Last Updated
14 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amir Lerman

M.D.

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • Patients must be identified in one of the four groups outlined in "study population description."

Exclusion Criteria

  • Other co-morbidities that would make the testing not possible.
  • Women who have had a mastectomy and would not have an arm that could be occluded during the reactive hyperemia portion of the Peripheral arterial tonometry testing.

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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