Comparison effect of Metformin and combination of acid folic and myo-inositol in poly cystic ovary syndrome
Phase 3
- Conditions
- Infertility, Polycystic ovary syndrome.
- Registration Number
- IRCT20201219049758N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 140
Inclusion Criteria
First IVF
No histoty of ovarian manipulation
Lack of male infertility factor
Patency of fallupian tubes
No history of smoking
Exclusion Criteria
History of IVF
histoty of ovarian manipulation
male infertility factor
No patency of fallupian tubes
history of smoking
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improving fertility in patients with polycystic ovary syndrome. Timepoint: Before starting the drug from three months before the start of the IVF cycle until the puncture and then before the puncture then comparison of two drug in fertilization rate. Method of measurement: HCG, Ultrasound.
- Secondary Outcome Measures
Name Time Method Body Mass Index, Fertilization rate, Abortion rate, EP rate, OHSS rate, Ovum count, Ovum quality, Embryo count, , Embryo quality, Follicle count,Follicle size. Timepoint: Patients took the drug three months before the start of the IVF cycle until the puncture, Body Mass Index was measured before and after the drug was completed. Method of measurement: Body Mass Index: weight(kg) on height(cm2), Fertility: HCG and ultrasound, Abortion: HCG and ultrasound, EP: HCG and ultrasound, OHSS: ultrasound, Follicle size: ultrasound, Follicle count: ultrasound, ovum count: microscopic and embryologist, ovum quality: microscopic and embryologist, Embryo count: microscopic and embryologist, Embryo quality: microscopic and embryologist.