Pharmacogenetics for Severe Mood Disorders: A Randomised Controlled Trial

Not Applicable

Recruiting

• Conditions: Severe Mood Disorders; Major Depressive Disorder; Bipolar Disorder; Mental Health - Depression; Public Health - Health service research

• Registration Number: ACTRN12621001374853
• Lead Sponsor: The University of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-11
• Last Update Posted: 6 November 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

1.Have a primary diagnosis of MDD or BD.
2.Are currently experiencing a manic, mixed or depressive episode (for those with
BD diagnosis)
3.Are admitted or referred to the participating site
4.Have been prescribed or willing to be prescribed an antidepressant and/or
mood stabiliser
5.Are aged 18 years or older
6.Sufficiently proficient in English to enable completion of the self-reported
study assessment tools.

Exclusion Criteria

1.Are unable to give informed consent
2.If they are clinically unstable or lacking decision-making capacity in the opinion of their
treating clinician
3.Are unwilling to provide a buccal swab sample
4.Have significant neurological disorders (e.g. stroke, dementia, Parkinson’s disease)
5.Have liver disease (e.g. hepatitis, cirrhosis)
6.Are pregnant or planning on becoming pregnant during the trial period

Study & Design

• Study Type: Interventional
• Study Design: Not specified