Reducing the stress Response to definite airway weaning with a Comparative Study Between Dexmedetomidine and Lignocaine drugs in patients who have undergone Surgery
Not Applicable
- Conditions
- Health Condition 1: 8- Other Procedures
- Registration Number
- CTRI/2020/11/029326
- Lead Sponsor
- KMCH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged between 20 to 65 years belonging to ASA 1 and ASA 2 undergoing elective surgical procedures in general surgery, gynaecology and ENT surgery with minimum anticipated duration of 60 minutes requiring endotracheal intubation were included in the study.
Exclusion Criteria
Patients with cardio-respiratory, renal, hepatic dysfunctions necessating post-operative mechanical ventilation, metabolic disorder, bleeding disorder, severe hypovolemia, neurological deficit, emergency surgery, morbid obesity, pregnancy, difficult airway and who are on antihypertensives, antiarrthymics, psychotropics and allergic medications to any drugs were excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main aim of the study was to compare the effectiveness of single dose of Dexmedetomidine and Lignocaine in alleviating haemodynamic and airway responses during extubation and recovery. This study also focuses on the effects of drugs on observing the time to emergence and time to tracheal extubation, post-operative complications and undesirable effects of the study drug.Timepoint: Baseline, 1,2,3,4,5,10,15 minutes
- Secondary Outcome Measures
Name Time Method This study also focuses on the effects of drugs on observing the time to emergence and time to tracheal extubation, post-operative complications and undesirable effects of the study drug.Timepoint: Baseline, 1,2,3,4,5,10,15 minutes