Effect of Tranexamic Acid On intraoperative Bleeding
Phase 2
- Conditions
- Intraoperative Bleeding during Rhinoplasty.
- Registration Number
- IRCT2015092824241N1
- Lead Sponsor
- Vice Chancellor for Research of Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
Normotensive patients scheduled for elective open rhinoplasty aged 16-42 years without a history of bleeding diathesis with ASA (American Society of Anesthesiologists) class of either I or II. Exclusion Criterai: patients with uncontrolled hypertension; history of hypersensitivity to tranexamic acid; brain vascular diseases; coronary artery diseases; cardiac dysrhythmia; liver/kidney or metabolic disorders; patients with ASA class of either III or IV.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Estimated amount of intraoperative bleeding. Timepoint: During surgery (starting from the incision till wound closure). Method of measurement: The volume of blood suctioned during a surgery is calculated by subtracting the amount of irrigation fluid used during a surgery from the total amount of fluid gathered in suction canister at the end of surgery. The volume of blood absorbed by 4*4 inch gauzes during an operation is calculated by multiplying the number of gauzes completely soaked with blood by 10 milliliters (an estimated average of blood absorbed per gauze). These two values are then added to estimate the total intraoperative volume of blood loss.
- Secondary Outcome Measures
Name Time Method -. Timepoint: -. Method of measurement: -.