Evaluation of perflubutane-enhanced ultrasonography agent sonazoid for the detection of the distribution pf local anesthesia after ultrasound-guided nerve block

Onishi Eiko0 sites16 target enrollmentJuly 27, 2020

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Not specified
Sponsor: Onishi Eiko
Enrollment: 16
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

We demonstrated that 100-fold diluted perflubute allowed clear, real-time, and continuous visualization of local anesthetic spread in ultrasound images in RSB and PVB. However, in a deeper block such as Epi, perfluobutane could not show contrast enhancement. Further investigation is needed in the future.

Registry

who.int

Start Date

July 27, 2020

End Date

November 20, 2020

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Onishi Eiko

Eligibility Criteria

Inclusion Criteria

•(1\) Patients needed nerve block
•(2\) American Society of Anesthesiologists (ASA) classification1\-3
•(3\) Over the age of 20
•(4\) Make and Female

Exclusion Criteria

•(1\) Patients having a pain, neuropathic pain, or paralysis at the site of nerve block
•(2\) Egg allergy, or contrast medium allergy
•(3\) histry of anaphylaxy shock
•(4\) Patients with arteriovenous shunt in cardia and lung
•(5\) Severe heart disease
•(6\) Severe pulmonary disease
•(7\) Patients with pregnacy or nursing
•(8\) Emergency surgery
•(9\) Patients considered ineligible for this study