NCT04847726已完成不适用
Perfluorobutane-enhanced Ultrasound as a Diagnostic Tool for Hepatocellular Carcinoma in Individuals With High Risk: Intraindividual Comparison With Sulfur Hexafluoride-enhanced Ultrasound
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 2
- 主要终点
- Diagnostic accuracy for HCC: non-inferiority test
研究概览
简要总结
Intra-individual comparison of diagnostic performance of CEUS With perfluorobutane and sulfur hexafluoride for HCC in high-risk Individuals, and their role in the diagnostic algorithm of HCC.
详细描述
The investigators would compare the diagnostic performance for HCC at high-risk individuals between both USG contrast agents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •high-risk for HCC (liver cirrhosis, chronic hepatitis B)
- •treatment-naive hepatic nodule (>= 1cm) on preceding CT, MR or ultrasound
排除标准
- •severe cardiopulmonary dysfunction
- •pregnancy
- •refusal to enroll study
结局指标
主要结局
Diagnostic accuracy for HCC: non-inferiority test
时间窗: up to 3 months
The per-lesion diagnostic accuracy for HCC of CEUS with perfluorobutane and sulfur hexafluoride using the same diagnostic criteria (arterial phase hyperenehancement with mild and late (≥ 60 sec) washout).
次要结局
- Diagnostic performance of perfulorobutane enhanced USG using different definition of washout(up to 3 months)
研究者
Jeong Min Lee
Professor
Seoul National University Hospital
研究点 (2)
Loading locations...
相似试验
已完成
不适用
A Prospective Comparison of Fluoroscopic, Sonographic or Combined Approach for Renal Access in Percutaneous NephrolithotomyUrolithiasisNCT02266381The First Affiliated Hospital of Guangzhou Medical University450
已完成
1 期
Evaluation of perflubutane with ultrasound-guided nerve blockJPRN-jRCTs021200011Onishi Eiko16
终止
不适用
Accuracy of Ultrasound for Detecting Residual Fragments During RIRSStone, KidneyUltrasound Therapy ComplicationsNCT05535816University of California, San Francisco40
Unknown
不适用
Comparing the Diagnostic Efficacy of Different Suction Techniques for EUS-FNB of Pancreatic Solid LesionsPancreatic MassNCT04100941Changhai Hospital300
已完成
不适用
Contrast-enhanced ultrasound with Perflubutane in massive postpartum hemorrhagepostpartum hemorrhageJPRN-UMIN000010541Kyoto University, Graduate School of Medicine Obstetrics and Gynecogy18