A clinical trial to study the effects of combination therapy with two drugs, oral prednisolone and fluticasone nasal spray in patients with chronic rhinosinusitis with polyposis
Not Applicable
- Conditions
- Health Condition 1: R52- Pain, unspecified
- Registration Number
- CTRI/2019/12/022305
- Lead Sponsor
- JAWAHARLAL NEHRU HOSPITAL AND RESEARCH CENTRE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients >18 years willing to take part and
give written informed consent.
2. Patients with complains of nasal discharge,
nasal obstruction, facial pain and decreased
sense of smell for more than 12 weeks.
3. Patients with presence of bilateral moderate
to large nasal polyps on Nasal Endoscopy.
Exclusion Criteria
1. Patients not giving consent for our study.
2. Patients who have received medical treatment
in last 4 months.
3. Patients who have undergone surgery in last 6
months.
4. Patients with contraindications and
hypersensitivity to steroids.
5. Female patients who are pregnant, lactating
or planning to become pregnant.
6. Patients with co-morbidities like
Hypertension, Diabetes mellitus, Asthma,
Tuberculosis, Epilepsy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in nasal obstruction score after treatmentTimepoint: Reduction in Visual Analog Symptom score in follow up at 3 weeks and 2 months from baseline
- Secondary Outcome Measures
Name Time Method Reduction in Nasal Endoscopic and CT Scan Nose and Paranasal sinuses score after treatmentTimepoint: Reduction in Lund and Mackay scoring of Nasal Endoscopy and CT Scan of Nose and Paranasal Sinuses in follow up at 3 weeks and 2 months from baseline.