Comparison of the effect of pure fat injection vs injection of enriched fat with stem cells in repairing age-related changes on the face
Not Applicable
Completed
- Conditions
- Facial fat injection due to aging changesNot Applicable
- Registration Number
- ISRCTN17134958
- Lead Sponsor
- Islamic Azad Medical Sciences University, Mashhad branch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 72
Inclusion Criteria
1. Women aged 20 to 60 years
2. Body mass index (BMI) 18.5 to 25 kg/m²
3. Symmetrical face
Exclusion Criteria
1. Systemic diseases (such as diabetes and hypertension)
2. Taking immunosuppressive drugs (such as corticosteroids), anticoagulants (such as aspirin), and non-steroidal anti-inflammatory drugs (such as ibuprofen)
3. History of allergy to anesthetics
4. History of psychiatric disorders (such as body dysmorphic disorder and anorexia nervosa, etc)
5. Weight gain or weight loss diet
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference between the two groups in terms of the effect of pure autologous fat grafting vs adipose tissue-derived stem cell-enriched autologous fat grafting on age-related changes on the face, measured using the investigator-generated checklist, medical photography, and a panel of referees consisting of two female general practitioners, a plastic surgeon unrelated to the patient's treatment process and an experienced hairdresser, evaluated before and after the procedure and at intervals of 6, 12, and 18 months.
- Secondary Outcome Measures
Name Time Method Age and patient demographic information evaluated using a demographic questionnaire at baseline