Does caffeine enhance the circadian light sensitivity in the human retina?
Recruiting
- Conditions
- Influence of caffeine on melanopsin sensitivity in the retina
- Registration Number
- DRKS00027398
- Lead Sponsor
- Centre for ChronobiologyTransfaculty Research Platform Molecular and Cognitive Neurosciences (MCN)Psychiatric Hospital of the University of Basel (UPK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
BMI <18.5 >29.9; Chronotoype (Morningness-Evening Questionnaire) (<31 >69); Sleep quality (Pittsburgh Sleep Quality Index, PSQI) (>5); Substance abuse (Alcohol Use Disorders Identification Test, AUDIT) (>7); Depressive symptoms (Center for Epidemiologic Studies Depression scale, CES-D) (>17); Habitual caffeine intake consumption (Caffeine intake questionnaire) (<100 mg/day >300 mg/day)
Exclusion Criteria
Schwangerschaft; hormonelle Verhuetungsmittel, BMI <18.5 > 29.9; exklusive Verwendung von Kontaktlinsen; hohe Myopie; Zeitzonenreisen in den letzten drei Monaten; Schichtarbeit in den letzten drei Monaten; Teilnahme in anderen klinischen Studien; Koffeinempfindlichkeit
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Melanopsin sensitivity (assayed using the pupillary light reflex)
- Secondary Outcome Measures
Name Time Method Salivary melatonin, mean pupil size, subjective sleepiness, vigilance performance