Clinical observation of multiple dose use of tranexamic acid in patients with rheumatoid arthritis after total knee arthroplasty
- Conditions
- Total knee arthroplasty
- Registration Number
- ITMCTR1900002510
- Lead Sponsor
- Guanghua Hospital, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Diagnosed as rheumatoid arthritis according to the Classification of Rheumatoid Arthritis revised by the American College of Rheumatology in 1978 and the classification of rheumatoid arthritis by the American College of Rheumatology and the European Union of Rheumatology in 2010. Kellgren-LawrenceX line is graded III or IV;
2. Aged 50-75 years;
3. Initial unilateral TKA surgery;
4. Perioperative TXA antifibrinolytic therapy;
5. Preoperative hemoglobin, The coagulation function is normal.
1. With severe cardiovascular disease (such as myocardial infarction, atrial fibrillation, angina pectoris, heart failure, etc.), cerebrovascular disease (cerebral infarction, brain Bleeding, etc., need long-term oral anticoagulant drugs (such as aspirin, warfarin, clopidogrel, etc.).
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
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