Clinical observation for tranexamic acid multiple use after total knee arthroplasty and its effect on inflammatory factors

Guanghua Hospital, Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1) The primary unilateral total knee arthroplasty is required for the end stage of primary OA or RA;
•2) Aged 55-80 years old;
•3) perioperative patients receiving tranexamic acid antifibrinolytic therapy;
•4) Preoperative hemoglobin, normal coagulation function.

•1) Patients with secondary osteoarthritis other than primary knee osteoarthritis or rheumatoid arthritis (eg post-traumatic osteoarthritis, gouty osteoarthritis, hemophilic osteoarthritis, tuberculosis, Arthritis, ankylosing spondylitis, etc.);
•2) Primary OA or RA requiring bilateral total knee arthroplasty;
•3) suffering from severe cardiovascular diseases (such as myocardial infarction, atrial fibrillation, angina pectoris, heart failure, etc.), cerebrovascular diseases (cerebral infarction, cerebral hemorrhage, etc.), requiring long-term oral anticoagulant drugs (such as aspirin, warfarin) , clopidogrel, etc.);
•4) Diagnosis of hemophilia or coagulopathy.

发起方

Guanghua Hospital, Shanghai University of Traditional Chinese Medicine