TCTR20190114001尚未招募4 期
Effectiveness of extended dose of tranexamic acid for 48 hours vs single dose perioperative tranexamic acid on reduction of blood loss after primary total knee arthroplasty: A randomized controlled trial
Faculty of Medicine, Prince of Songkla university0 个研究点目标入组 94 人开始时间: 2019年1月14日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 94
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •Patients undergoing primary unilateral total knee arthroplasty
- •Diagnosis of primary osteoarthritis of knee
- •Age less than 85 years old
排除标准
- •1.Previous surgery around the affected knee
- •2.Complex TKA requiring the use of stemmed prosthesis
- •3.Use of anticoagulant at the time of admission
- •4.Documented allergy to drug in the study
- •5.History of deep vein thrombosis or pulmonary embolism
- •6.Abnormal coagulation at admission
- •International normalized ration > 1.5
- •Partial thromboplastin time > 1.4x normal
- •Platelet < 50,000/microL
- •7.Abnormal liver function test
- •Aspartate transaminase/Alanine transaminase > 3x normal
- •Alkaline phosphatase > 5x normal
- •8.Calculated glomerular filtration rate < 30 mL/min
- •9.History of acute coronary syndrome or cerebrovascular accident in the past 12 months
- •10.Active cancer
- •11.Use of drug with interaction with Tranexamic acid; eg. Tretinoin, Estrogen, Oral contraceptive pill
研究者
相似试验
已完成
不适用
effectiveness of Tranexamic acid in blood loss during and after cesarean sectiocaesarean section.Single delivery by caesarean sectionIRCT2014100419396N1Hormozgan University of Medical Sciences200
招募中
4 期
Clinical observation of multiple dose use of tranexamic acid in patients with rheumatoid arthritis after total knee arthroplastyTotal knee arthroplastyITMCTR1900002510Guanghua Hospital, Shanghai University of Traditional Chinese Medicine
已完成
2 期
Assessment the efficacy of Tranexamic Acid in reducing blood loss after laminectomy and postrolateral fusion of spineAnticoagulant drug.Anticoagulant antagonists, vitamin K and other coagulantsIRCT2017020913947N6Vice chancellor for research, Tabriz University of Medical Sciences, Golgasht St, Tabriz, Iran50
招募中
不适用
Assessment the efficacy of Tranexamic Acid in reducing blood loss after laminectomy and postrolateral fusion of spineTopical administration of TXA helps control bleeding and prevents unwanted side effects.Spinal stenosis, lumbar regionM48.06IRCT20120527009878N6Deputy of Research of Tabriz University50
尚未招募
4 期
To assess the effect of Tranexamic acid in cure of a pigment disorderCTRI/2018/07/014952Hindu Mission Hospital