The effectiveness of melatonin on migraine headaches
Phase 3
- Conditions
- migraine.Migraine
- Registration Number
- IRCT20170316033099N12
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Confirmed migraine as per the indices of the International Headache Society
Age between 18 and 65 years
Residence in South Khorasan Province
An average of two migraine attacks per month
A minimum of one-year history of migraine
The first migraine attack occurring before age 50
Informed consent for participation
Exclusion Criteria
History of headaches lasting longer than 15 days a month
History of any neurological disorder other than migraine
Allergy to the study medications
Presence of debilitating diseases such as cancer and autoimmune diseases, advanced diabetes, etc.
Pregnancy and lactation
Persistent headache
History of seizures and epilepsy
History of neurological and mental illnesses
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain severity. Timepoint: study onset, fourth week, eighth week, and twelfth week. Method of measurement: visual analog scale.;Pain duration. Timepoint: fourth week, eighth week, and twelfth week. Method of measurement: patient's report.;Number of migraine attacks. Timepoint: fourth week, eighth week, and twelfth week. Method of measurement: patient's report.
- Secondary Outcome Measures
Name Time Method