Evaluating the Causative Insects in the Cases With Severe Insect Sting Allergy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Mean wheal diameters of skin prick test of local and imported insect allergens
研究概览
简要总结
Study the causative insect by skin prick test and sIgE to wasp, bee and fire ants are important but false positive by crossreactivity can occur. sIgE to recombinant venom allergen is proposed to help in finding the causative insect.
详细描述
Insect sting allergy from insects in Hymenoptera is not uncommon. The reaction maybe very severe and life threatening. To find the cause of insect sting allergy is important in prevention and specific treatment such as immunotherapy. The skin prick test and sIgE of these insects may have cross reactions so it is difficult to be interpreted.
The usage of sIgE recombinant venom allergen can benefit in separate cross reaction and dual allergy reaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cases with severe insect sting allergy reactions
排除标准
- •Without other severe systemic diseases
- •Not pregnant or lactation
结局指标
主要结局
Mean wheal diameters of skin prick test of local and imported insect allergens
时间窗: 12 months
Compare Mean wheal diameters of skin prick test of local and imported insect allergens at different concentrations
次要结局
- specific IgE level to stinging insect allergen and recombinant venom allergens(12 months)
研究者
Nualanong Visitsunthorn
Professor
Mahidol University