Efficacy Of Copper To Reduce Acquisition Of Microbes and Healthcare-acquired Infections

Not Applicable

Completed

• Conditions: Healthcare-acquired Infection
• Interventions: Other: Copper-alloy surfaced patient care objects

• Registration Number: NCT01565798
• Lead Sponsor: Medical University of South Carolina

Brief Summary

CONTEXT: Healthcare-acquired infections (HAI) cause substantial patient morbidity and mortality. Commonly touched items in the patient care environment harbor microorganisms that may contribute to HAI risk. Thus, reduction in the surface bioburden may be an effective strategy to reduce HAI. Inherent biocidal capabilities of copper surfaces offer a theoretical advantage to conventional cleaning, as disinfection is continuous rather than episodic.

OBJECTIVE: Determine whether placement of copper-alloy surfaced objects in an intensive care unit (ICU) reduce risk of HAI.

DESIGN: An intention to treat study where patients are sequentially placed into rooms with or without copper-alloy surfaced objects.

SETTING: The ICUs of three hospitals, a tertiary academic hospital, an academic cancer center, and a Veteran's Administration Medical Center.

PATIENTS: Any patient 18 years of age or older who required admission to an ICU at a study hospital is eligible for placement into a study room if available.

INTERVENTION: Placement of copper-alloy surfaced objects in an ICU room. MAIN OUTCOME MEASURE: Rate of incident HAI and/or colonization with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) in each type of room.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Status Verified: 2011-12
• Study First Submitted: 2012-03-26
• Study First Submitted QC: 2012-03-28
• Study First Posted: 2012-03-29
• Last Update Submitted: 2016-03-23
• Last Update Posted: 2016-03-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 614

Inclusion Criteria

patients 18 years and older requiring admission to an ICU at one of the study sites were eligible

Exclusion Criteria

• less than 18 years of age or
• pregnant

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Copper Surfaced Room	Copper-alloy surfaced patient care objects	Patients sequentially randomized to this arm were admitted to an ICU room with copper surfaced objects.

Primary Outcome Measures

Name	Time	Method
Rate of incident HAI and/or colonization with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) in each type of room.	July 2010 to June 2011 (up to 1 year)	Patients prospectively followed from ICU admission to hospital discharge for acquisition of HAI and/or colonization with MRSA or VRE

Secondary Outcome Measures

Name	Time	Method
Microbial burden and risk of HAI	July 2010 to June 2011 (up to 1 year)	The risk of HAI among patients admitted to ICU will be assessed by microbial burden of environment.

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States