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Optimal Stent Duration After Ureteroscopy

Not Applicable
Conditions
Ureteral Stent
Interventions
Device: Ureteral stent
Registration Number
NCT06045962
Lead Sponsor
Mayo Clinic
Brief Summary

The purpose of this study is to determine how soon ureteral stents can be safely removed following surgery.

Detailed Description

The rationale for this study is to determine if there is a difference in symptoms or complications among patients undergoing uncomplicated ureteroscopy for stone removal with shorter indwelling stent duration. Currently there are only a few small studies exploring the optimal duration of stent placement after stent placement and no multicenter randomized control trials. The investigation aim is to determine if earlier ureteral stent removal will reduce urinary symptoms after stent removal and improve quality of life without increasing risk of negative side effects. Using questionnaires for stent related symptoms the researchers will assess stent indwelling time effect on patient reported side effects.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
172
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Uncomplicated Ureteroscopy and Stent Placement for 3-5 daysUreteral stentAfter standard of care ureteroscopic procedure stents will be left indwelling for 3-5 days
Uncomplicated Ureteroscopy and Stent Placement for 7-9 daysUreteral stentAfter standard of care ureteroscopic procedure stents will be left indwelling for 7-9 days
Primary Outcome Measures
NameTimeMethod
Change in Urinary Symptom ScoresPost-operative day 2-3 and 2-3 days after stent removal

The urinary symptoms will be assessed using the self-reported Canadian Endourology Group Stent Symptom Score. Seven item questionnaire to assess urinary stent symptoms using a 5-point Likert scale; higher score indicated worse outcome.

Secondary Outcome Measures
NameTimeMethod
Change in Pain ScoresPost-operative day 2-3 and 2-3 days after stent removal

Pain score as indicated in the self-reported Canadian Endourology Group Stent Symptom Score questionnaire with a scale of 0-10 (10 being the worst)

Change in Quality of lifePost-operative day 2-3 and 2-3 days after stent removal

Change as calculated using the Wisconsin "Living With Kidney Stones" Questionnaire, which is a validated document assessing the quality of life of kidney stone patients. Likert scale 1-5 on 28 items total score range 28-140, with a lower score being associated with a lower quality of life.

Return to work30 days

Number of days participants return to work

Complications30 days

Number of subjects to experience complications assessed by telephone, epic messages, ER visits related to procedure, unanticipated provider visits, and hospitalizations.

Trial Locations

Locations (11)

Johns Hopkins University

🇺🇸

Baltimore, Maryland, United States

University of Arizona

🇺🇸

Tucson, Arizona, United States

Mayo Clinic Arizona

🇺🇸

Phoenix, Arizona, United States

University of California San Diego

🇺🇸

San Diego, California, United States

University of North Carolina

🇺🇸

Chapel Hill, North Carolina, United States

University of British Columbia

🇨🇦

Vancouver, British Columbia, Canada

Mayo Clinic Minnesota

🇺🇸

Rochester, Minnesota, United States

Vanderbilt University

🇺🇸

Nashville, Tennessee, United States

Cleveland Clinic

🇺🇸

Cleveland, Ohio, United States

University of Montreal

🇨🇦

Montréal, Quebec, Canada

Montefiore Medical Center

🇺🇸

Bronx, New York, United States

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