A micro randomised trial (MRT) to test the effects of app-based motivational messages on physical activity and on heart rate via smartphone app compliance in patients with vulnerable coronary artery plaques.

The University of Sydney0 个研究点目标入组 58 人开始时间: 2022年5月20日最近更新: 2024年2月27日

适应症

试验速览

暂无简介。

•1.Intervention group participants from the LIVEPLUS study (ANZCTR registration: ACTRN12620001151921).
•2.Adults who can competently use a smartphone (running iOS or Android)
•3.Presence of Low attenuation plaque on Coronary Computed Tomography Angiography
•4.18-80 years of age
•5.BMI greater than or equal to 22.0 kg/m2
•6.Have no contraindications for the LIVEPLUS study
•7.Able to give full informed consent

•People from the Control group participants from the LIVEPLUS study (ANZCTR registration: ACTRN12620001151921) will be excluded.
•Additional exclusion criteria for the parent LIVEPLUS study are as follows:
•1. History or clinical manifestation of any other significant metabolic, hematologic, pulmonary, cardio- vascular, gastrointestinal, neurologic, immune, hepatic, renal, urologic disorders, or cancer that, in opinion of the investigator, would make the candidate ineligible for the study
•2.Non-MRI-compatible implanted devices or implants
•3.Estimated glomerular filtration rate (eGFR) less than 30mL/kg/1.73m2
•4.Inability to exercise via supine ergometer
•5.Claustrophobia
•6.Contraindications for adenosine: Sinus node disease (e.g. sick sinus syndrome, symptomatic sinus bradycardia), second- or third- degree heart blocks, unstable angina, bronchospasm (e.g. asthma), heart transplant recipient, history of seizure disorder
•7.Contraindications for glyceryl trinitrate: Known nitrate hypersensitivity, severe anaemia, severe aortic or mitral stenosis, hypotension defined as resting systolic blood pressure equal to 89 mmHg.
•8.Not suitable for CT coronary angiography due to contraindications
•9.Psychiatric or behavioural problems (history of drug and alcohol abuse, eating disorder)
•10.Breast feeding or pregnant women, or those intending to become pregnant before the scheduled end of the intervention
•11.Concurrent participation in any other interventional study.

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