NCT04519411撤回不适用
Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- Mayo Clinic
- 主要终点
- Transpulmonary pressure
研究概览
简要总结
The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- — 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 0-17 years of age, 10 kg or greater, with suspected or confirmed Covid-19 respiratory failure requiring endotracheal intubation and mechanical ventilation admitted to Mayo Clinic Hospital, St. Mary's Campus Pediatric Intensive Care Unit.
排除标准
- •Patients <10 kg
- •Patients with pre-existing chronic mechanical ventilation (chronic respiratory failure)
- •Patients with known esophageal disease (strictures, known esophageal anatomic abnormalities)
- •Patients with severe coagulopathy (for which placement of esophageal balloon or other gastric tube via nose or mouth is contraindicated)
- •Patients who are pregnant (as determined by standard pregnancy testing criteria for Pediatric ICU admission).
结局指标
主要结局
Transpulmonary pressure
时间窗: Through study complication, usually 2 weeks
Numerical data
次要结局
未报告次要终点
研究者
Stephen J. Gleich
Principal Investigator
Mayo Clinic
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