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Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure

Not Applicable
Withdrawn
Conditions
COVID 19
Interventions
Diagnostic Test: Transpulmonary pressure measurements
Registration Number
NCT04519411
Lead Sponsor
Mayo Clinic
Brief Summary

The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Patients 0-17 years of age, 10 kg or greater, with suspected or confirmed Covid-19 respiratory failure requiring endotracheal intubation and mechanical ventilation admitted to Mayo Clinic Hospital, St. Mary's Campus Pediatric Intensive Care Unit.
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Exclusion Criteria
  • Patients <10 kg
  • Patients with pre-existing chronic mechanical ventilation (chronic respiratory failure)
  • Patients with known esophageal disease (strictures, known esophageal anatomic abnormalities)
  • Patients with severe coagulopathy (for which placement of esophageal balloon or other gastric tube via nose or mouth is contraindicated)
  • Patients who are pregnant (as determined by standard pregnancy testing criteria for Pediatric ICU admission).
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Intubated pediatric patients with COVID-19 respiratory failureTranspulmonary pressure measurements-
Primary Outcome Measures
NameTimeMethod
Transpulmonary pressureThrough study complication, usually 2 weeks

Numerical data

Secondary Outcome Measures
NameTimeMethod
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