Comparison of Stepwise PEEP vs Sustained Inflation Recruitment Maneuvers on Postoperative Oxygenation and Atelectasis in Bariatric Surgery Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Ain Shams University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Postoperative lung aeration
Study Overview
Brief Summary
Male and female patients Undergoing laparoscopic bariatric surgeries will be subjected for lung recruitment at end of surgery before emergence from anesthesia by two different methods . to evaluate which might be safer and more effective
Detailed Description
In the SI group:, the anesthesiologist adjust the ventilator to manual ventilation mode and ad¬just The ventilator will be switched to manual mode, and the airway pressure-limiting valve will be set to 30 cmH₂O. A sustained manual inflation was then applied by gradually squeezing the anesthesia reservoir bag over 3-5 seconds until a peak airway pressure (Ppeak) of 30 cmH₂O was achieved. This pressure was maintained continuously for 30 seconds. Following the maneuver, mechanical ventilation was resumed with positive end-expiratory pressure (PEEP) back to 5 cmho In the IP group:, alveolar recruitment will be performed as follows: ventilation will be set to pressure control mode and the driving pressure maintained at 10 cmH2O with an initial PEEP of 5 cmH2O, respiratory rate 8-10, I:E 1-1PEEP will be then increased by 5 cmH2O ev¬ery 30 s until the Ppeak reached 30 cmH2O (so peep will reach 20), held for 30 s , then PEEP will be gradually reduced at intervals of 5 cmH2O down to 5 cmH2O, when initial volume control ventilation will be resumed. In the incremental PEEP group, PEEP was increased stepwise by 5 cmH₂O every 3-5 breaths until a peak airway pressure of 30 cmH₂O was achieved, after which mechanical ventilation was resumed with maintenance PEEP. The total duration of the recruitment maneuver was approximately 60-90 seconds.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Anesthesiologists (ASA) physical status II, of either sex Age ≥18 y.
- •Undergoing laparoscopic bariatric surgeries; sleeve gastrectomy, mini gastric bypass
- •BMI (35-60)
Exclusion Criteria
- •Pre-existing severe pulmonary disease
- •Baseline hypoxemia SpO₂ <92% on room air
- •History of barotrauma
- •Previous pneumothorax
- •Known pulmonary bullae or emphysematous blebs
Arms & Interventions
group SI
receive 30 cmH₂O sustained inflation for 30seconds
Intervention: sustained inflation recruitement (Procedure)
group IP
receive PEEP was increased stepwise by 5 cmH₂O every 3-5 breaths until a peak airway pressure of 30 cmH₂O
Intervention: Stepwise PEEP (Procedure)
Outcomes
Primary Outcomes
Postoperative lung aeration
Time Frame: in the post-anesthesia care unit 15 minutes after extubation
limited-zone lung ultrasound scoring system
Secondary Outcomes
- Postoperative oxygenation(in the post-anesthesia care unit 15 minutes after extubation)
- Oxygen requirement in PACU(in the post-anesthesia care unit 15 minutes after extubation)
Investigators
Amr Fouad
Assistant Professor
Ain Shams University
