Which local anesthetic drug is ideal for spinal anesthesia for short duration surgeries like inguinal hernia surgery ?0.5% isobaric Levobupivacaine or 0.5% isobaric Ropivacine?

Not yet recruiting

• Conditions: Unilateral inguinal hernia, without obstruction or gangrene, (2) ICD-10 Condition: 4||Measurement and Monitoring,

• Registration Number: CTRI/2022/11/047664
• Lead Sponsor: MALBAR MEDICAL COLLEGE

Brief Summary

A comparative study of intrathecal 0.5% levobupivacaine versus 0.5% ropivacaine  in unilateral inguinal hernia surgeries was proposed as a study to compare duration of motor and sensory blockade as primary objective. Secondary objective being to compare the onset time to maximum sensory and motor blockade and hemodynamic parameters and our hypothesis is that levobupivacaine has prolonged duration of sensory and motor blockade which is better for prolonged surgeries and ropivacaine has shorter duration of motor blockade which is preferred for faster recovery and early ambulation and hence the latter can be administered for daycare surgeries. It is also beneficial in context of decreasing the incidence of urinary retention .

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-12
• Last Update Posted: 2022-11-22

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1.ASA 1 & 2 patients 2.Scheduled for unilateral inguinal hernia surgeries.

Exclusion Criteria

• 1.Patients not willing to participate in the study 2.
• Contra indications to spinal anaesthesia ( INR>1.3, platelet count <75000) 3.
• ASA 3,4 patients 4.
• Neurological diseases like multiple sclerosis, lumbar disc herniation etc...
• Allergy to local anaesthetics.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare duration of motor and sensory blockade of intrathecal 0.5% isobaric levobupivacaine with 0.5% isobaric ropivacaine	After giving spinal blood pressure and heart rate will be checked every one minute for 10 mins and every 5 mins for next 1 hour and then every 15 mins until the end of the surgery.Sensory and motor blockade will be assessed every 3 min for 15 min and every 10 min for 45 min,every 15 min for 90 min and finally 30 min thereafter until sensory block regress to S2 dermatome.

Secondary Outcome Measures

Name	Time	Method
1.onset of action	2.time to maximum sensory and motor blockade

Trial Locations

Locations (1)

MALABAR MEDICAL COLLEGE HOSPITALAND RESEARCH CENTRE; 🇮🇳 Kozhikode, KERALA, India

MALABAR MEDICAL COLLEGE HOSPITALAND RESEARCH CENTRE

🇮🇳Kozhikode, KERALA, India

DR FIFINA K K

Principal investigator

9539442824

fifna.latheef@gmail.com