Coenzyme Q10 and Dentoalveolar Cyst

Phase 2

Active, not recruiting

• Conditions: Cyst, Jaw
• Interventions: Drug: control group; Drug: Coenzyme Q10

• Registration Number: NCT05873673
• Lead Sponsor: Fayoum University

Brief Summary

10 patients in each group will undergo cyst removal under local anesthesia. After cyst removal, the cystic cavity will be filled with placebo gel in the control group or coenzyme gel in the coenzyme group.

Bone density and volume will be assessed by cone beam CT immediately postoperative and 6months later for all patients

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-05-15
• Study First Submitted QC: 2023-05-15
• Study First Posted: 2023-05-24
• Study Start: 2023-06-11
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-26
• Primary Completion: 2025-03-01
• Last Update Posted: 2025-03-03
• Study Completion: 2025-04-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Adult patients with critical-size jaw cysts
• Medically stable
• No cystic lesion recurrence

Exclusion Criteria

• Cystic lesion recurrence
• Medical problem

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	control group	-
coenzyme group	Coenzyme Q10	-

Primary Outcome Measures

Name	Time	Method
bone density	6 months	measure the bone density of new bone in the cystic cavity at 6 months by cone beam CT

Secondary Outcome Measures

Name	Time	Method
bone volume	6months	measure the bone volume in the defect by cone beam CT at 6 months

Trial Locations

Locations (1)

Fayoum University; 🇪🇬 Fayoum, Egypt