A study to compare 2 medications-Phenylephrine and Norepinephrine to prevent fall in blood pressure caused after giving spinal anaesthesia in patients undergoing Caesarean section.
- Conditions
- Health Condition 1: O295- Other complications of spinal andepidural anesthesia during pregnancy
- Registration Number
- CTRI/2020/03/023761
- Lead Sponsor
- AIIMS Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 95
Grade 3 and 4 as per Lucas classification of urgency of caesarean section
Pregnant females undergoing Caesarean section under spinal anaesthesia
Age 18-35 years
ASA grade 2
Gestational age more than 37 weeks with singleton pregnancy
Not consenting for the study
ASA grades 3,4
Body weight <50kgs, >100kgs
Height <140cm, >170cm
Any pregnancy complications like pregnancy-induced hypertension, gestational diabetes,abruptio placenta,
placenta previa
Any medical diseases like Diabetes mellitus, Hypertension, Cardiac diseases, Severe anemia, Peripheral
vascular diseases.
Failed subarachnoid block
Contraindication to Spinal Anaesthesia
Patients on monoamine oxidase inhibitors and anti-depressants
Spinal Deformities
Diagnosed preoperative fetal compromise
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of post-spinal hypotension in women receiving phenylephrine versus norepinephrine infusion.Timepoint: Every minute after spinal anaesthesia upto delivery of newborn.
- Secondary Outcome Measures
Name Time Method To compare incidences of maternal bradycardia, fetal acid-base balance, Apgar score and the requirements of vasopressor dosesTimepoint: Every minute after spinal anaesthesia upto delivery of newborn.