Role of 18F-FDG PET/CT in Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- comparison of pet -ct finding with ct finding
研究概览
简要总结
The objective of the study is to assess the value of PET/CT in diagnosis, staging, response evaluation, and relapse monitoring of gastric cancer.
详细描述
gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer mortality worldwide (1) It carries a poor prognosis, with a 5-year survival of only 20%-30% (2) Clinical staging, based mainly on imaging, is critical in determining the best treatment.There is a widely accepted consensus of the usefulness of FDG PET/CT in staging and restaging of gastric cancer. According to evidence-based data, this modality can evaluate gastric cancer more accurately and is helpful for evaluation of tumor biologic characteristics, detection of lymph node and distant metastases, assessment of tumor response to therapy(9).
retrospective and prospective study will conducted at Sohag oncology hospital, nuclear medicine unit& Assuit university hospital, nuclear medicine unit including 50 patients in 12 months .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed as GC on surgically resected specimens;
- •Patients with gastric and extragastric metastasis.
- •patients with gastric cancer either operated or not.
排除标准
- •Patients with second malignancy.
- •Patient without proven pathology of cancer stomach.
- •Severely ill patient (patient with disturbed conscious level, or couldn't lay supine during the imaging).
- •uncontrolled diabetic patient with blood glucose level more than 200mg\dl.
- •pregnant women
结局指标
主要结局
comparison of pet -ct finding with ct finding
时间窗: base line
The 18F-FDG PET/CT scan is visually estimated in the patients included in the study and quantitatively assessed by estimation of standardized uptake value(suv max). Statistical analysis of the included quantitative data.
次要结局
未报告次要终点
研究者
Sara Saber Ahmed
assisstant lecturer
Sohag University