NCT01155739
Completed
Not Applicable
Etude Prospective Sur l'Impact de l'Utilisation de la Procalcitonine Dans l'évaluation de la Poursuite ou de l'arrêt du Traitement Antibiotique Empirique Lors de péritonites et d'Infections Intra-abdominales
University of Lausanne Hospitals1 site in 1 country162 target enrollmentJune 2009
ConditionsSecondary or Tertiary Peritonitis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Secondary or Tertiary Peritonitis
- Sponsor
- University of Lausanne Hospitals
- Enrollment
- 162
- Locations
- 1
- Primary Endpoint
- antibiotic treatment length, hospitalisation length without antibiotic, infection recurrence, antibiotic cost
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
Procalcitonin level used for determining length of antibiotic treatment in peritonitis and intra-abdominal infections. Hypothesis is that length of antibiotic use can be shortened by this method.
Detailed Description
Prospective randomized trial
Investigators
Nicolas DEMARTINES
professor of surgery
University of Lausanne Hospitals
Eligibility Criteria
Inclusion Criteria
- •More than 18 yo
- •Patient requiring surgery for peritonitis or intra-abdominal infection following: perforation, necrosis, previous operation...
- •Mannheim Peritonitis score \> 14
- •SIRS present
- •Probability of survival \> 72h
- •Informed consent by patient/relatives
Exclusion Criteria
- •Long date corticoid treatment
- •Immunosuppression
- •Thyroid medullary carcinoma
- •Anaphylactic shock
- •Acute hepatic deficiency
Outcomes
Primary Outcomes
antibiotic treatment length, hospitalisation length without antibiotic, infection recurrence, antibiotic cost
Time Frame: at one month and during hospital stay
Study Sites (1)
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