NCT01155739已完成不适用
Etude Prospective Sur l'Impact de l'Utilisation de la Procalcitonine Dans l'évaluation de la Poursuite ou de l'arrêt du Traitement Antibiotique Empirique Lors de péritonites et d'Infections Intra-abdominales
University of Lausanne Hospitals1 个研究点 分布在 1 个国家目标入组 162 人开始时间: 2009年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 162
- 试验地点
- 1
- 主要终点
- antibiotic treatment length, hospitalisation length without antibiotic, infection recurrence, antibiotic cost
研究概览
简要总结
Procalcitonin level used for determining length of antibiotic treatment in peritonitis and intra-abdominal infections. Hypothesis is that length of antibiotic use can be shortened by this method.
详细描述
Prospective randomized trial
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •More than 18 yo
- •Patient requiring surgery for peritonitis or intra-abdominal infection following: perforation, necrosis, previous operation...
- •Mannheim Peritonitis score > 14
- •SIRS present
- •Probability of survival > 72h
- •Informed consent by patient/relatives
排除标准
- •Long date corticoid treatment
- •Immunosuppression
- •Thyroid medullary carcinoma
- •Anaphylactic shock
- •Acute hepatic deficiency
结局指标
主要结局
antibiotic treatment length, hospitalisation length without antibiotic, infection recurrence, antibiotic cost
时间窗: at one month and during hospital stay
次要结局
未报告次要终点
研究者
Nicolas DEMARTINES
professor of surgery
University of Lausanne Hospitals
研究点 (1)
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