Chest Radiography in COVID-19 Patients

Completed

• Conditions: Covid19

• Registration Number: NCT04485338
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

To assess the prognostic performance of the RALE score with respect to duration of ventilation, and to describe changes in the RALE score over time.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-07-23
• Study First Submitted QC: 2020-07-23
• Study First Posted: 2020-07-24
• Study Start: 2020-08-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-09-01
• Status Verified: 2022-02
• Last Update Submitted: 2022-02-15
• Last Update Posted: 2022-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 139

Inclusion Criteria

• Admitted to an ICU participating in this study between December 1, 2019 and May 31, 2020
• Having had received invasive ventilation
• Having had received at least one chest radiograph under invasive ventilation
• Confirmed novel coronavirus diseases (COVID-19)

Exclusion Criteria

• Age < 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The prognostic capacity of the Radiographic Assessment of Lung Edema (RALE) score of the first CXR under invasive ventilation in patients with severe COVID-19.	90 days

Secondary Outcome Measures

Name	Time	Method
The prognostic capacity of changes in the RALE score of consecutive CXRs under invasive ventilation in patients with severe COVID-19	90 days
Number of ventilator-free day and alive at day 28 (VFD)	28 days

Trial Locations

Locations (1)

Amsterdam UMC location AMC; 🇳🇱 Amsterdam, Netherlands