A Randomized controlled study of neonates undergoing endotracheal intubation with high nasal flow oxygen VS standard care
Overview
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- DrHima Chandana Mankala
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- to observe first successful intubation attempt in neonates undergoing endotracheal intubation with high nasal flow oxygen vs neonates receiving standard care
Overview
Brief Summary
This study aims to evaluate the effectiveness of high-flow nasal oxygen in improving the success of the first endotracheal intubation attempt in neonates, compared with standard care. By closely observing clinical outcomes in both groups, the study seeks to determine whether the continuous oxygen delivery provided by high-flow nasal therapy helps maintain better oxygenation and physiological stability during the procedure. The investigation will assess not only the rate of first-attempt success but also associated factors such as heart rate changes, oxygen desaturation episodes, and overall intubation conditions. Through this comparison, the study intends to generate evidence on whether integrating high-flow nasal oxygen into neonatal airway management can enhance procedural safety and reduce complications during intubation.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 0.00 Day(s) to 28.00 Day(s) (—)
- Sex
- All
Inclusion Criteria
- •all eligible neonates undergoing endotracheal intubation in KIMS NICU.
Exclusion Criteria
- •infants with oromaxillary and airway anomalies.
Outcomes
Primary Outcomes
to observe first successful intubation attempt in neonates undergoing endotracheal intubation with high nasal flow oxygen vs neonates receiving standard care
Time Frame: to observe first successful intubation attempt in neonates undergoing endotracheal intubation with high nasal flow oxygen vs neonates receiving standard care immediately after the intubation attempt -10 mins
Secondary Outcomes
- To assess if time to desaturation is prolonged with high nasal flow oxygen via nasal prongs(10 mins of study)
Investigators
HIMA CHANDANA MANKALA
KEMPEGOWDA INSTITUTE OF MEDICAL SCIENCES