Variations in Optic Nerve Sheath diameter along with change in intra abdominal pressure and end tidal CO2 in laparoscopic surgery
Not Applicable
Not yet recruiting
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/02/031333
- Lead Sponsor
- Department of Anaesthesiology and Critical Care JNMC AMU Aligarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anesthesiologists (ASA) physical status I and II, scheduled to undergo elective surgery under general anaesthesia requiring tracheal intubation
Exclusion Criteria
(1)Patients having increased Intracranial pressure(ICP).
(2)Any optic nerve disease or known orbital cavity tumor/malignancy
(3)Known orbital injury or prior ocular surgery
(4)History of neurological disorders, hyperthyroidism.
(5)Pregnant/lactating female patient.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To observe the changes in Optic Nerve Sheath Diameter(ONSD) using USG following acute elevations of IAP and simultaneous changes in end-tidal CO2 <br/ ><br> <br/ ><br>Timepoint: The changes in ONSD will be measured with the corresponding changes in IAP, end-tidal CO2 and MAP during following time intervals after tracheal intubation and before the starting of surgical procedure, <br/ ><br>5 mins after stabilisation of intra abdominal pressure of 10mm of Hg and 15mm of Hg and 10 mins after desufflation of gas. <br/ ><br>Further, the changes in ONSD corresponding to changes in IAP will be measured after standardizing/bringing the End-tidal CO2 to normal level(35-40 mm Hg) <br/ ><br>
- Secondary Outcome Measures
Name Time Method To observe changes in Mean Arterial Pressure(MAP) intraoperatively during acute elevations of IAP. <br/ ><br>To identify which is more sensitive parameter between End-tidal CO2 and Intra-abdominal pressure(IAP) on the ONSD. <br/ ><br>Timepoint: The changes in ONSD will be measured with the corresponding changes in IAP, end-tidal CO2 and MAP during following time intervals after tracheal intubation and before the starting of surgical procedure, <br/ ><br>5 mins after stabilisation of intra abdominal pressure of 10mm of Hg and 15mm of Hg and 10 mins after desufflation of gas. <br/ ><br>Further, the changes in ONSD corresponding to changes in IAP will be measured after standardizing/bringing the End-tidal CO2 to normal level(35-40 mm Hg) <br/ ><br>