ong-term effects of routine morphine infusion in newborns who received ventilatory support

Completed

• Conditions: gevoeligheid warmte/ koude, functioneren HPA-as; detection thresholds; stress response; 10028920

• Registration Number: NL-OMON29866
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 192

Inclusion Criteria

Children who participated in a larger neonatal randomized, double-blind, placebo-controlled trial in the Erasmus MC-Sophia Rotterdam and Isala Clinics Zwolle in the period 2000-2003 (MW-NWO-940-31-048).

Exclusion Criteria

Mental handicap

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>· Detection thresholds for warmth and cold will be assessed by the thermal<br /><br>sensory analyzer (TSA)<br /><br>· Stress responsiveness will be assessed by collection of salivary cortisol<br /><br>· Chronic pain will be assessed by The Chronic Pain Questionnaire and Pain<br /><br>diary</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>