Effect of low-dose intrathecal (within the spinal space) morphine as a part of multimodal analgesia (which combines various groups of medications for pain relief) in patients aged 18 to 65 years undergoing cardiac surgery by cutting of breast bone.
- Conditions
- Health Condition 1: I39- Endocarditis and heart valve disorders in diseases classified elsewhere
- Registration Number
- CTRI/2024/06/068299
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients aged 18 to 65 years undergoing midline sternotomy for cardiac surgeries, New York Heart Association grade II-III patients
Patient refusal to consent, contraindications to intrathecal analgesia such as infection at the injection site, coagulopathy,
and allergy to morphine, pre-existing chronic pain: taking routine analgesics, patients with a history of chronic opiate abuse, patients with psychiatric disorders, patients with previous surgery in thoracic vertebral region, preexisting neurological condition (spinal cord injury, multiple sclerosis, etc.), patients with BMI more than or equal to 35, patients with severe respiratory disease, those expected to be on elective mechanical ventilation for more than 6 hours postoperatively, patients with renal dysfunction (Serum creatinine more than 1.5 mg/dl).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method