Identifying factors that predict the need for increased tissue removal during breast-conserving surgery for breast cancer, in order to reduce the need for a second surgery
Not Applicable
Completed
- Conditions
- Breast cancer patients operated on using breast-conserving surgerySurgery
- Registration Number
- ISRCTN32164784
- Lead Sponsor
- und University
- Brief Summary
2019 Abstract results in https://doi.org/10.1158/1538-7445.SABCS18-P3-13-03 Presented at 2018 San Antonio Breast Cancer Symposium (added 03/09/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34611702/ (added 01/12/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 779
Inclusion Criteria
Female patients operated with breast-conserving surgery with a final diagnosis of in situ or invasive cancer at Skåne University Hospital 2015-2016 for study cohort or 2017 for validation cohort or at Kristianstad hospital in 2017 for external validation
Exclusion Criteria
1. Male gender
2. Primary operation not coded as breast-conserving surgery
3. Neoadjuvant treatment
4. Benign final pathology result
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> All measured retrospectively and extracted from medical records:<br> 1. Number of patients with non-radical breast conserving surgery after first procedure<br> 2. Preoperative tumor and patient characteristics such as age, BMI, breast side and size, screening detection, palpability of tumor, location in breast, distance from mamilla, lymph node palpability and status, previous breast operations, radiographic characteristics and size, biopsy results<br>
- Secondary Outcome Measures
Name Time Method <br> All measured retrospectively and extracted from medical records:<br> Post-operative tumor and patient characteristics such as method of operation, indication method, pathology results from tumor and axilla, weight of excised lump and operation time<br>