The effect of Omeprazole suspension on gastric pH of ICU patients
Not Applicable
- Conditions
- erosion (acute) of stomach.Gastric ulcer
- Registration Number
- IRCT2016062120592N6
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
age of =16 yrs of age; anticipated stay of =72 hrs in ICU; required mechanical ventilation more than 48 hrs; APACHE II score =11; have a nasogastric or orogastric tube in place; have at least one additional risk factor for upper GI bleeding Exclusion criteria: status of no CPR; delay of >48 hrs from time of initial eligibility; history of gastric surgery; allergy to omeprazole; active GI bleeding; significant risk of swallowing blood; admission for upper GI surgery; known upper GI Lesions that might bleed; inability to take a suspension by nasogastric tube;end-stage liver disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean gastric pH. Timepoint: before and 1-2.5 hrs after drug administration. Method of measurement: pH meter.
- Secondary Outcome Measures
Name Time Method Active upper GI bleeding. Timepoint: every day up to 14 days. Method of measurement: Gastroccult test.