Investigation of the applicability of dry powder inhalation in children with cystic fibrosis

Completed

• Conditions: cystic fibrosis; mucoviscidosis; 10024970

• Registration Number: NL-OMON40571
• Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- A physician*s diagnosis of CF
- 4 to 14 years of age
- Informed consent from the parent(s)/guardian(s)
- Assent from the child (informed consent when >=12 years of age)

Exclusion Criteria

No exclusion criteria are formulated.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the ability of a child to achieve a proper<br /><br>inhalation manoeuvre with the test inhaler, which is reflected in the pressure<br /><br>drop they create over the inhaler upon inhalation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>From the (duration of the) pressure drop, various inspiratory parameters will<br /><br>be calculated per airflow resistance. The incidence of obstructions in the oral<br /><br>cavity upon inhalation will be expressed as percentage of the total number of<br /><br>observations.</p><br>