Dry powder inhalation in patients with Parkinson’s disease.
Completed
- Conditions
- Ability of a Parkinson’s patient to use the inhaler correctly during off periods.
- Registration Number
- NL-OMON24879
- Lead Sponsor
- Department of Pharmaceutical Technology and Biopharmacy, Faculty of Mathematics and Natural Sciences, University of Groningen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Predictable off periods.
Recognizable off periods for themselves and others.
Exclusion Criteria
Cognitive dysfunction, which precludes good understanding of instructions and/or informed consent.
Current treatment with apomorphine or duodopa by pump.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The parameter that describes whether or not a Parkinson’s patient is capable of using the inhaler correctly is the pressure drop (s)he creates over the inhaler upon inhalation.
- Secondary Outcome Measures
Name Time Method Peak and mean inspiratory flow rate (PIFR and MIFR).<br>Acceleration towards peak inspiratory flow rate (flow increase rate: FIR).<br>Inhaled volume.<br>Total inhalation time.<br>