Investigation of the applicability of dry powder inhalation in patients with Parkinson*s disease.

Completed

• Conditions: Parkinsons disease; Parkinson; 10028037

• Registration Number: NL-OMON38957
• Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Predictable off periods.
Recognizable off periods for themselves and others.
At least 2 years of levodopa use.
Signed informed consent.
Diagnosed with Parkinson*s disease
Age 18 or older.

Exclusion Criteria

Cognitive dysfunction, which precludes good understanding of instructions and/or informed consent.
Current treatment with apomorphine or duodopa by pump.
Any active pulmonary disease.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>the main study parameter is the ability of a Parkinson*s patient to use the<br /><br>inhaler correctly during off periods. The parameter that describes whether or<br /><br>not a Parkinson*s patient is capable of using the inhaler correctly is the<br /><br>pressure drop (s)he creates over the inhaler upon inhalation. For the Twincer*<br /><br>a pressure drop of at least 2 kPa is needed, but the target pressure drop is 4<br /><br>kPa.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>