Effect of probiotic, curcumin, and curcumin-probiotic on quality of life, anxiety, stress, and depressio

Phase 3

Recruiting

• Conditions: Metabolic Syndrome.; Metabolic syndrome; E88.81

• Registration Number: IRCT20220315054289N2
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

Aged 30 - 65 years Overweight (BMI between 25 to 29.9) or obese (BMI over 30) individuals with metabolic syndrome based on ATP III criteria
Not suffering from metabolic, endocrine, or cardiovascular disease (except diabetes, dyslipidemia, and hypertension) at baseline
Not suffering from kidney, liver, or systemic diseases at the beginning of the study
Not infected with Covid-19 or any other infections for 3 months before the study
No history of hospitalization for 3 months prior to the study
Has not used antibiotics for 3 months before beginning the study
Has not taken curcumin and probiotic supplements, or supplements for 3 months before the study

Exclusion Criteria

Pregnancy
Lactating

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of Life. Timepoint: At the beginning of the study (before the intervention) and the end of the study (8 weeks after the intervention). Method of measurement: SF-36 questionnaire.;Depression, Anxiety and Stress. Timepoint: At the beginning of the study (before the intervention) and the end of the study (8 weeks after the intervention). Method of measurement: DASS-21 questionnaire.