NCT03348566已完成不适用
Fish and Marine Fatty Acids, Genetic Signatures of Diet Adaptation, and Long-term Weight Change
Harvard School of Public Health (HSPH)0 个研究点目标入组 22,000 人开始时间: 2015年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 22,000
- 主要终点
- weight changes
研究概览
简要总结
the investigators tested whether genetic variants near FADS cluster, which were recently identified to be signatures of adaptation to fish- and n-3 PUFAs-rich diet, interacted with these dietary factors on long-term change of body mass index (BMI).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •11,323 women of European ancestry.
- •Informed consent was obtained from all participants. The DNA extraction methods, quality control measures,
- •SNPs genotyping and imputation data are available .
- •Both cases and controls with genotyping data are available based on GWASs
排除标准
- •participants without genetic data
结局指标
主要结局
weight changes
时间窗: 6-10 years
long term weight changes: this study measured body weight at baseline (1990) and follow up body weight in 2000. The long term body weight was defined as changes from baseline to follow up endpoint
次要结局
未报告次要终点
研究者
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