Voice Adaptive Training for Adults With Aphasia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 4
- 主要终点
- Change in naming on the Boston Naming Test (BNT)
研究概览
简要总结
Rising life expectancy is leading to a rising incidence of strokes worldwide. Approximately one third of people who had a stroke live with a communication disorder, aphasia, which is associated with the largest negative relationship to quality of life. In chronic stages, people with aphasia (PwA) often do not receive any rehabilitation, despite treatment being shown to significantly reduce impairment. In contrast to existing computerized aphasia treatment, VoiceAdapt is an innovative and motivating application for PwA that provides adaptive and context-aware training lessons via speech interaction on the mobile device. A user-centred design process and motivational gamification ensure long-term engagement in training. Through providing an autonomously usable and low-cost tool, VoiceAdapt will positively affect PwA's self-esteem and social inclusion, leading to higher quality of life.
详细描述
Purpose:
The purpose of the study proposed in this ethics application is to examine the impact of an adaptive speech-language treatment app, created using principles of user-centred design, on language and communication outcomes of people with aphasia (PwA) within a randomized controlled trial.
Background:
Nearly one third of individuals who have a stroke will present with aphasia, a communication impairment that affects the ability to speak, understand, read and write. People with aphasia (PwA) have been shown to demonstrate more limitations in their participation in daily activities, lower quality of life and a higher incidence of depression relative to post-stroke individuals without aphasia, even when other factors such as physical ability, social support and well-being were similar.
The overall goals of the VoiceAdapt research project are to: 1) conduct a needs survey with PwA and speech-language pathologists (SLPs); 2) develop an app employing a user-centred design process; and 3) conduct a randomized controlled trial. Using user-centred design, end users and stakeholders (PwA, therapists and formal/informal caregivers) will be engage din a needs survey during the technology development process. Outcomes will be analyzed to elaborate implications for decision makers as to how to implement such adaptive training environments in stroke rehabilitation. This aspect of the research (i.e., Goals 1 & 2) will be carried out by consortium members in Austria and Germany. Only the randomized controlled trial (Goal 3), which is the subject of the present application, will be conducted at the University of Alberta and the University of Toronto.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •be at least 6 months post onset of a single stroke in the left hemisphere
- •have aphasia of mild to moderate severity (Aphasia Quotient ≥ 30 on WAB--R) with a prominent verbal expression impairment.
- •pass screenings of visual perception (BORB), hearing (pure tone screening with portable audiometer), and basic cognitive functioning (Raven's Coloured Progressive Matrices)
- •speak English as a primary language.
- •be willing to commit to participation for study duration
排除标准
- •Currently participating in individual (one-on-one) speech-language therapy
结局指标
主要结局
Change in naming on the Boston Naming Test (BNT)
时间窗: baseline; 7 weeks; 13 weeks
Naming performance (out of 60) on the BNT
次要结局
- Change in Aphasia Quotient on the Western Aphasia Battery-Revised (WAB-R)(baseline; 7 weeks; 13 weeks)
- Change in score on the Stroke and Aphasia Quality of Life Scale (SAQOL-39)(baseline; 7 weeks; 13 weeks)
- Change in score on the Communication Effectiveness Index (CETI)(baseline; 7 weeks; 13 weeks)