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临床试验/NCT03369860
NCT03369860Unknown不适用

Basi Neuro-cognitive Dell'Interazione Motoria

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2017年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
发起方
入组人数
50
试验地点
1
主要终点
Reaction Times

研究概览

简要总结

The ability to interact with conspecifics is crucial in life, yet there is no consensus on the underlying cognitive and neural mechanisms beyond those associated with imitative behaviors. This project aims to define a coherent model of non-imitative (complementary) motor interactions. The investigators hypothesize that these might be substantially based on the ability to integrate one's own and a partner's action within a unitary, dual- person (dyadic), motor plan that incorporates a shared goal.

With a novel "minimally-joint" paradigm the investigators will test this hypothesis and measure with behavioral measures (i.e., reaction times) whether the supposedly automatic tendency to imitate others is modulated by the need to coordinate with a partner to achieve a shared goal.

This paradigm will be also applied during a functional MRI experiment to describe the underlying neurophysiological patterns; using dynamic causal modeling the investigators will measure how the brain regions relevant for dyadic motor control are functionally linked.

This converging experimental strategy will permit to compare competing psychological and neural models of motor interactions in healthy participants, opening new experimental avenues for studies in adult neuropsychological patients and in children with typical and atypical social development.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •right handed; no contraindication to MRI

排除标准

  • •contraindication to MRI

研究组 & 干预措施

Healthy Subjects

Experimental

Healthy Subjects take part in the experimental manipulation

干预措施: Interactivity of Experimental Condition (Behavioral)

结局指标

主要结局

Reaction Times

时间窗: 1 year

The investigators will compare Reaction Times of participants recorded during Joint Action with those recorded in Non-Joint individual condition.

BOLD activations

时间窗: 1 year

The investigators will study the neurofunctional activations indexed by the Blood Oxygen Level Dependent (BOLD) recorded during Joint Action will be compared to the Non-Joint actions

次要结局

未报告次要终点

研究者

发起方
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
申办方类型
Other
责任方
Sponsor

研究点 (1)

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