Improvement following acute paraquat poisoning due to antioxidant therapy

Not Applicable

• Conditions: Acute paraquat intoxication

• Registration Number: SLCTR/2008/016
• Lead Sponsor: South Asian Clinical Toxicology Research Collaboration

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 20 August 2024

Recruitment & Eligibility

• Status: Complete: follow up complete
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Consecutive patients who get admitted to General Hospital, Matara following history of acute exposure to paraquat and symptoms suggestive of acute exposure to paraquat will be selected for the study

Exclusion Criteria

• Unconscious patients • Pregnant mothers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of total antioxidant status in plasma after administration of Intra Venous vitamin C+placebo or vitamin C + NAC<br> [First five consecutive days of acute exposure to paraquat<br>]<br>

Secondary Outcome Measures

Name	Time	Method
Improvement of survival<br> [Two months after acute exposure to paraquat<br>]<br>